Researchers recently found that a membrane protein found in bacteria has a similar structure and functions as a group of proteins that are responsible for remodeling and rebuilding the cell membrane in humans . The phage shock protein (Psp) system was discovered in bacteria about 30 years ago and was identified at that time as a reaction of the Escherichia coli bacteria to an infection with special viruses, the so-called bacteriophages. that its function of protecting the cell membrane exceeds the specific response to bacteriophage infection.
Osmotic stress, heat, cell toxins or defects in the membrane envelope can also trigger the stress reaction. ”Today we know that the Psp system is activated in response to numerous types of membrane stress. Dirk Schneider, head of the membrane proteins working group at JGU. “That’s why we decided to take a closer look at the core proteins of the Psp system.